2JEI

The Molecular Basis of Selectivity of Nucleoside Triphosphate Incorporation Opposite O6-Benzylguanine by Sulfolobus solfataricus DNA Polymerase IV: Steady-state and Pre-steady-state Kinetics and X- Ray Crystallography of Correct and Incorrect Pairing

Summary for 2JEI

• Entry DOI: 10.2210/pdb2jei/pdb
• Related: 1JX4 1JXL 1N48 1N56 1RYR 1RYS 1S0M 1S0N 1S0O 1S10 1S97 1S9F 2AGO 2AGP 2AGQ 2ASD 2ASJ 2ASL 2ATL 2AU0 2BQ3 2BQR 2BQU 2BR0 2C22 2C28 2C2D 2C2E 2C2R 2J6S 2J6T 2J6U 2JEF 2JEG 2JEJ
• Descriptor: DNA POLYMERASE IV, 5'-D(*GP*GP*GP*GP*GP*AP*AP*GP*GP*AP *TP*TP*CP*T)-3', 5'-D(*TP*CP*AP*C BZGP*GP*AP*AP*TP*CP*CP *TP*TP*CP*CP*CP*CP*C)-3', ... (6 entities in total)
• Functional Keywords: dna replication, mutator protein, 06-benzylguanine, nucleotidyltransferase, dna-directed dna polymerase, dpo4, magnesium, polymerase, dna damage, dna repair, alkylating agents, translesion synthesis, transferase, dna-binding, metal-binding
• Biological source: SULFOLOBUS SOLFATARICUS
• Total number of polymer chains: 3
• Total formula weight: 51617.71

Authors

Eoff, R.L.,Angel, K.C.,Kosekov, I.D.,Egli, M.,Guengerich, F.P. (deposition date: 2007-01-17, release date: 2007-03-13, Last modification date: 2023-12-13)

• Primary citation: Eoff, R.L.,Angel, K.C.,Egli, M.,Guengerich, F.P.; Molecular Basis of Selectivity of Nucleoside Triphosphate Incorporation Opposite O6-Benzylguanine by Sulfolobus Solfataricus DNA Polymerase Dpo4: Steady-State and Pre-Steady-State Kinetics and X-Ray Crystallography of Correct and Incorrect Pairing.; J.Biol.Chem., 282:13573-, 2007; PubMed: 17337730; DOI: 10.1074/JBC.M700656200

Experimental method

X-RAY DIFFRACTION (2.39 Å)