2J9Z

Tryptophan Synthase T110 mutant complex

Summary for 2J9Z

Entry DOI	10.2210/pdb2j9z/pdb
Related	1A50 1A5A 1A5B 1A5S 1BEU 1BKS 1C29 1C8V 1C9D 1CW2 1CX9 1FUY 1K3U 1K7E 1K7F 1K7X 1K8X 1K8Y 1K8Z 1KFB 1KFC 1KFE 1KFJ 1KFK 1QOP 1QOQ 1TJP 1TTP 1UBS 1WBJ 2CLE 2CLF 2CLI 2CLK 2CLL 2CLM 2CLO 2J9X 2J9Y 2TRS 2TSY 2TYS 2WSY
Descriptor	TRYPTOPHAN SYNTHASE ALPHA CHAIN, TRYPTOPHAN SYNTHASE BETA CHAIN, PYRIDOXAL-5'-PHOSPHATE, ... (5 entities in total)
Functional Keywords	aromatic amino acid biosynthesis, tryptophan biosynthesis, synthase carbon- oxygen lyase, amino-acid biosynthesis, lyase, allosteric enzyme, pyridoxal phosphate
Biological source	SALMONELLA TYPHIMURIUM More
Total number of polymer chains	2
Total formula weight	71871.81
Authors	Blumenstein, L.,Domratcheva, T.,Niks, D.,Ngo, H.,Seidel, R.,Dunn, M.F.,Schlichting, I. (deposition date: 2006-11-16, release date: 2007-12-04, Last modification date: 2011-07-13)
Primary citation	Blumenstein, L.,Domratcheva, T.,Niks, D.,Ngo, H.,Seidel, R.,Dunn, M.F.,Schlichting, I. Betaq114N and Betat110V Mutations Reveal a Critically Important Role of the Substrate Alpha-Carboxylate Site in the Reaction Specificity of Tryptophan Synthase. Biochemistry, 46:14100-, 2007 Cited by PubMed: 18004874 DOI: 10.1021/BI7008568 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (1.8 Å)

Structure validation