2J9J

Atomic-resolution Crystal Structure of Chemically-Synthesized HIV-1 Protease Complexed with Inhibitor JG-365

Summary for 2J9J

Entry DOI	10.2210/pdb2j9j/pdb
Related PRD ID	PRD_000228
Descriptor	PROTEASE, INHIBITOR MOLECULE JG365, SULFATE ION, ... (7 entities in total)
Functional Keywords	hydrolase-hydrolase inhibitor complex, protease, hydrolase, high resolution, rna-directed dna polymerase, aspartyl protease, human immunodeficiency virus 1, hydrolase- hydrolase inhibitor complex, hydrolase/hydrolase inhibitor
Biological source	HUMAN IMMUNODEFICIENCY VIRUS 1 More
Total number of polymer chains	3
Total formula weight	22855.72
Authors	Malito, E.,Shen, Y.,Johnson, E.C.B.,Tang, W.J. (deposition date: 2006-11-11, release date: 2007-08-28, Last modification date: 2023-12-13)
Primary citation	Johnson, E.C.B.,Malito, E.,Shen, Y.,Pentelute, B.,Rich, D.,Florian, J.,Tang, W.J.,Kent, S.B.H. Insights from Atomic-Resolution X-Ray Structures of Chemically Synthesized HIV-1 Protease in Complex with Inhibitors. J.Mol.Biol., 373:573-, 2007 Cited by PubMed: 17869270 DOI: 10.1016/J.JMB.2007.07.054 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (1.04 Å)

Structure validation