2J8G

Crystal structure of the modular Cpl-1 endolysin complexed with a peptidoglycan analogue (E94Q mutant in complex with a tetrasaccharide- pentapeptide)

Summary for 2J8G

Entry DOI	10.2210/pdb2j8g/pdb
Related	1H09 1OBA 2IXU 2IXV 2J8F
Descriptor	LYSOZYME, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-N-acetyl-beta-muramic acid-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ALANINE, ... (7 entities in total)
Functional Keywords	antimicrobial, muein hydrolase, bacteriolytic enzyme, pneumococcal cell wall degradation, lysozyme, hydrolase, glycosidase, multimodular
Biological source	BACTERIOPHAGE CP-1
Total number of polymer chains	1
Total formula weight	40349.51
Authors	Perez-Dorado, I.,Hermoso, J.A. (deposition date: 2006-10-25, release date: 2007-07-03, Last modification date: 2023-12-13)
Primary citation	Perez-Dorado, I.,Campillo, N.E.,Monterroso, B.,Hesek, D.,Lee, M.,Paez, J.A.,Garcia, P.,Martinez-Ripoll, M.,Garcia, J.L.,Mobashery, S.,Menendez, M.,Hermoso, J.A. Elucidation of the Molecular Recognition of Bacterial Cell Wall by Modular Pneumococcal Phage Endolysin Cpl-1. J.Biol.Chem., 282:24990-, 2007 Cited by PubMed: 17581815 DOI: 10.1074/JBC.M704317200 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (1.69 Å)

Structure validation