2J88

Hyaluronidase in complex with a monoclonal IgG Fab fragment

Summary for 2J88

• Entry DOI: 10.2210/pdb2j88/pdb
• Related: 1FCQ 1FCU 1FCV
• Descriptor: HYALURONONGLUCOSAMINIDASE, FAB, ... (4 entities in total)
• Functional Keywords: glycoprotein, glycosidase family 56, zymogen, allergen, 7- stranded (beta/alpha) tim barrel, hydrolase, glycosidase, immunoglobulin domain
• Biological source: APIS MELLIFERA (HONEY BEE); More
• Cellular location: Secreted: Q08169
• Total number of polymer chains: 3
• Total formula weight: 85001.18

Authors

Padavattan, S.,Schirmer, T.,Markovic-Housley, Z. (deposition date: 2006-10-23, release date: 2007-04-03, Last modification date: 2023-12-13)

• Primary citation: Padavattan, S.,Schirmer, T.,Schmidt, M.,Akdis, C.,Valenta, R.,Mittermann, I.,Soldatova, L.,Slater, J.,Mueller, U.,Markovic-Housley, Z.; Identification of a B-Cell Epitope of Hyaluronidase, a Major Bee Venom Allergen, from its Crystal Structure in Complex with a Specific Fab.; J.Mol.Biol., 368:742-, 2007; PubMed: 17374540; DOI: 10.1016/J.JMB.2007.02.036

Experimental method

X-RAY DIFFRACTION (2.6 Å)