2J7I

ATYPICAL POLYPROLINE RECOGNITION BY THE CMS N-TERMINAL SH3 DOMAIN. CMS:CD2 HETERODIMER

Summary for 2J7I

Entry DOI	10.2210/pdb2j7i/pdb
Related	1CDB 1GYA 1HNF 1L2Z 2BZ8 2J6F 2J6K 2J6O
Descriptor	CD2-ASSOCIATED PROTEIN, T-CELL SURFACE ANTIGEN CD2 (3 entities in total)
Functional Keywords	coiled coil, polymorphism, glycoprotein, cell adhesion, egfr downregulation, immunoglobulin domain, transmembrane, phosphorylation, adaptor protein, cms, cd2ad, membrane, sh3 domain, sh3-binding, sh3 domain recognition, protein binding
Biological source	HOMO SAPIENS (HUMAN) More
Cellular location	Cytoplasm, cytoskeleton : Q9Y5K6 Membrane; Single-pass type I membrane protein: P06729
Total number of polymer chains	4
Total formula weight	17063.33
Authors	Moncalian, G.,Cardenes, N.,Deribe, Y.L.,Spinola-Amilibia, M.,Dikic, I.,Bravo, J. (deposition date: 2006-10-09, release date: 2006-11-06, Last modification date: 2017-07-05)
Primary citation	Moncalian, G.,Cardenes, N.,Deribe, Y.L.,Spinola-Amilibia, M.,Dikic, I.,Bravo, J. Atypical Polyproline Recognition by the Cms N-Terminal Src Homology 3 Domain. J.Biol.Chem., 281:38845-, 2006 Cited by PubMed: 17020880 DOI: 10.1074/JBC.M606411200 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.9 Å)

Structure validation