2J67

The TIR domain of human Toll-Like Receptor 10 (TLR10)

2J67 の概要

• エントリーDOI: 10.2210/pdb2j67/pdb
• 分子名称: TOLL LIKE RECEPTOR 10 (2 entities in total)
• 機能のキーワード: tir, il-1, toll, tlr10, membrane, receptor, inflammatory response, toll-like receptor 10, innate immunity, immune response, leucine-rich repeat, glycoprotein, transmembrane
• 由来する生物種: HOMO SAPIENS (HUMAN)
• 細胞内の位置: Membrane; Single-pass type I membrane protein (By similarity): Q9BXR5
• タンパク質・核酸の鎖数: 2
• 化学式量合計: 42578.57

構造登録者

Stenmark, P.,Ogg, D.,Arrowsmith, C.,Berglund, H.,Busam, R.,Collins, R.,Edwards, A.,Ericsson, U.B.,Flodin, S.,Flores, A.,Graslund, S.,Hammarstrom, M.,Hallberg, B.M.,Holmberg Schiavone, L.,Hogbom, M.,Johansson, I.,Karlberg, T.,Kotenyova, T.,Magnusdottir, A.,Nilsson, M.E.,Nilsson-Ehle, P.,Nyman, T.,Persson, C.,Sagemark, J.,Sundstrom, M.,Uppenberg, J.,Thorsell, A.G.,Van Den Berg, S.,Wallden, K.,Weigelt, J.,Welin, M.,Nordlund, P. (登録日: 2006-09-26, 公開日: 2006-09-27, 最終更新日: 2023-12-13)

• 主引用文献: Nyman, T.,Stenmark, P.,Flodin, S.,Johansson, I.,Hammarstrom, M.,Nordlund, P.; The Crystal Structure of the Human Toll-Like Receptor 10 Cytoplasmic Domain Reveals a Putative Signaling Dimer.; J.Biol.Chem., 283:11861-, 2008; PubMed: 18332149; DOI: 10.1074/JBC.C800001200

実験手法

X-RAY DIFFRACTION (2.2 Å)