2J4C

Structure of human Butyrylcholinesterase in complex with 10mM HgCl2

Summary for 2J4C

• Entry DOI: 10.2210/pdb2j4c/pdb
• Related: 1EHO 1EHQ 1KCJ 1P0I 1P0M 1P0P 1P0Q 1XLU 1XLV 1XLW
• Descriptor: CHOLINESTERASE, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose, ... (10 entities in total)
• Functional Keywords: hydrolase, inhibition, glycoprotein, polymorphism, inorganic mercury, cholinesterase, serine esterase, disease mutation
• Biological source: HOMO SAPIENS (HUMAN)
• Total number of polymer chains: 1
• Total formula weight: 63153.70

Authors

Colletier, J.P.,Frasco, M.F.,Carvalho, F.,Guilhermino, L.,Stojan, J.,Fournier, D.,Weik, M. (deposition date: 2006-08-28, release date: 2007-03-27, Last modification date: 2023-12-13)

• Primary citation: Frasco, M.F.,Colletier, J.,Weik, M.,Carvalho, F.,Guilhermino, L.,Stojan, J.,Fournier, D.; Mechanisms of Cholinesterase Inhibition by Inorganic Mercury.; FEBS J., 274:1849-, 2007; PubMed: 17355286; DOI: 10.1111/J.1742-4658.2007.05732.X

Experimental method

X-RAY DIFFRACTION (2.75 Å)