2IYO

Structural characterization of a bacterial 6PDH reveals aspects of specificity, mechanism and mode of inhibition

Summary for 2IYO

Entry DOI	10.2210/pdb2iyo/pdb
Related	2IYP 2IZ0 2IZ1
Descriptor	6-PHOSPHOGLUCONATE DEHYDROGENASE, DECARBOXYLATING, 6-PHOSPHOGLUCONIC ACID, CACODYLATE ION, ... (4 entities in total)
Functional Keywords	oxidoreductase, 6-phosphogluconate dehydrogenase, nadp, pentose shunt, gluconate utilization
Biological source	LACTOCOCCUS LACTIS
Total number of polymer chains	1
Total formula weight	52914.34
Authors	Sundaramoorthy, R.,Iulek, J.,Hunter, W.N. (deposition date: 2006-07-21, release date: 2007-01-23, Last modification date: 2023-12-13)
Primary citation	Sundaramoorthy, R.,Iulek, J.,Barrett, M.P.,Bidet, O.,Ruda, G.F.,Gilbert, I.H.,Hunter, W.N. Crystal Structures of a Bacterial 6-Phosphogluconate Dehydrogenase Reveal Aspects of Specificity, Mechanism and Mode of Inhibition by Analogues of High-Energy Reaction Intermediates. FEBS J., 274:275-, 2007 Cited by PubMed: 17222187 DOI: 10.1111/J.1742-4658.2006.05585.X PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.4 Å)

Structure validation