2IXP

Crystal structure of the Pp2A phosphatase activator Ypa1 PTPA1 in complex with model substrate

Summary for 2IXP

• Entry DOI: 10.2210/pdb2ixp/pdb
• Related: 2IXN 2IXO
• Related PRD ID: PRD_000352
• Descriptor: SERINE/THREONINE-PROTEIN PHOSPHATASE 2A ACTIVATOR 1, SIN-ALA-ALA-PRO-LYS-NIT, SULFATE ION, ... (4 entities in total)
• Functional Keywords: pp2a phosphatase activator prolyl isomerase ptpa, prolyl containing peptide substrate analog, nuclear protein, isomerase-isomerase inhibitor complex, isomerase/isomerase inhibitor
• Biological source: SACCHAROMYCES CEREVISIAE (BAKER'S YEAST); More
• Total number of polymer chains: 8
• Total formula weight: 152737.53

Authors

Leulliot, N.,Vicentini, G.,Jordens, J.,Quevillon-Cheruel, S.,Schiltz, M.,Barford, D.,Van Tilbeurgh, H.,Goris, J. (deposition date: 2006-07-09, release date: 2006-07-31, Last modification date: 2023-12-13)

• Primary citation: Leulliot, N.,Vicentini, G.,Jordens, J.,Quevillon-Cheruel, S.,Schiltz, M.,Barford, D.,van Tilbeurgh, H.,Goris, J.; Crystal structure of the PP2A phosphatase activator: implications for its PP2A-specific PPIase activity.; Mol. Cell, 23:413-424, 2006; PubMed: 16885030; DOI: 10.1016/j.molcel.2006.07.008

Experimental method

X-RAY DIFFRACTION (2.8 Å)