2IWZ

Human mitochondrial beta-ketoacyl ACP synthase complexed with hexanoic acid

Summary for 2IWZ

Entry DOI	10.2210/pdb2iwz/pdb
Related	2C9H 2IWY 2IX4
Descriptor	3-OXOACYL-[ACYL-CARRIER-PROTEIN] SYNTHASE, HEXANOIC ACID, AMMONIUM ION, ... (4 entities in total)
Functional Keywords	mitochondria, mitochondrion, lipid synthesis, fatty acid synthesis, fatty acid biosynthesis, beta-ketoacyl acp synthase, transit peptide, acyltransferase, claisen condensation, kas, cerulenin, transferase, homo sapiens
Biological source	HOMO SAPIENS (HUMAN)
Total number of polymer chains	2
Total formula weight	93147.52
Authors	Christensen, C.E.,Kragelund, B.B.,von Wettstein-Knowles, P.,Henriksen, A. (deposition date: 2006-07-05, release date: 2007-02-06, Last modification date: 2023-12-13)
Primary citation	Christensen, C.E.,Kragelund, B.B.,von Wettstein-Knowles, P.,Henriksen, A. Structure of the Human Beta-Ketoacyl [Acp] Synthase from the Mitochondrial Type II Fatty Acid Synthase. Protein Sci., 16:261-272, 2007 Cited by PubMed: 17242430 DOI: 10.1110/PS.062473707 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (1.65 Å)

Structure validation