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2IBU

Crystallographic and kinetic studies of human mitochondrial acetoacetyl-CoA thiolase (T2): the importance of potassium and chloride for its structure and function

Summary for 2IBU
Entry DOI10.2210/pdb2ibu/pdb
Related2IB7 2IB8 2IB9 2IBW 2IBY
DescriptorAcetyl-CoA acetyltransferase, CHLORIDE ION, COENZYME A, ... (5 entities in total)
Functional Keywordsthiolase fold, potassium ion, chloride, beta-alpha-beta-alpha-beta-alpha-beta-beta topology, alpha-beta-alpha-beta-alpha layered structure, transferase
Biological sourceHomo sapiens (human)
Cellular locationMitochondrion: P24752
Total number of polymer chains4
Total formula weight169500.23
Authors
Haapalainen, A.M.,Wierenga, R.K. (deposition date: 2006-09-12, release date: 2007-04-03, Last modification date: 2023-11-15)
Primary citationHaapalainen, A.M.,Merilainen, G.,Pirila, P.L.,Kondo, N.,Fukao, T.,Wierenga, R.K.
Crystallographic and Kinetic Studies of Human Mitochondrial Acetoacetyl-CoA Thiolase: The Importance of Potassium and Chloride Ions for Its Structure and Function
Biochemistry, 46:4305-4321, 2007
Cited by
PubMed: 17371050
DOI: 10.1021/bi6026192
PDB entries with the same primary citation
Experimental method
X-RAY DIFFRACTION (1.9 Å)
Structure validation

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