2I6U

Crystal Structure of Ornithine Carbamoyltransferase complexed with Carbamoyl Phosphate and L-Norvaline from Mycobacterium tuberculosis (Rv1656) at 2.2 A

Summary for 2I6U

Entry DOI	10.2210/pdb2i6u/pdb
Descriptor	Ornithine carbamoyltransferase, SULFATE ION, PHOSPHORIC ACID MONO(FORMAMIDE)ESTER, ... (5 entities in total)
Functional Keywords	mycobacterium tuberculosis, ornithine carbamyoltransferase, carbamoyl phosphate, l-norvaline, structural genomics, psi, protein structure initiative, tb structural genomics consortium, tbsgc, transferase
Biological source	Mycobacterium tuberculosis
Cellular location	Cytoplasm (Probable): P0A5M8
Total number of polymer chains	3
Total formula weight	100447.40
Authors	Sankaranarayanan, R.,Moradian, F.,Cherney, L.T.,Garen, C.,Cherney, M.M.,James, M.N.G.,TB Structural Genomics Consortium (TBSGC) (deposition date: 2006-08-29, release date: 2007-06-26, Last modification date: 2023-08-30)
Primary citation	Sankaranarayanan, R.,Cherney, M.M.,Cherney, L.T.,Garen, C.R.,Moradian, F.,James, M.N. The crystal structures of ornithine carbamoyltransferase from Mycobacterium tuberculosis and its ternary complex with carbamoyl phosphate and L-norvaline reveal the enzyme's catalytic mechanism J.Mol.Biol., 375:1052-1063, 2008 Cited by PubMed: 18062991 DOI: 10.1016/j.jmb.2007.11.025 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.2 Å)

Structure validation