2I07

Human Complement Component C3b

Summary for 2I07

• Entry DOI: 10.2210/pdb2i07/pdb
• Descriptor: Complement C3b, alpha-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose, ... (4 entities in total)
• Functional Keywords: c3b consists of 12 domains, immune system
• Biological source: Homo sapiens (human); More
• Cellular location: Secreted: P01024 P01024
• Total number of polymer chains: 2
• Total formula weight: 176291.26

Authors

Janssen, B.J.C.,Christodoulidou, A.,McCarthy, A.,Lambris, J.D.,Gros, P. (deposition date: 2006-08-10, release date: 2006-10-24, Last modification date: 2023-08-30)

• Primary citation: Janssen, B.J.,Christodoulidou, A.,McCarthy, A.,Lambris, J.D.,Gros, P.; Structure of C3b reveals conformational changes that underlie complement activity.; Nature, 444:213-216, 2006; PubMed: 17051160; DOI: 10.1038/nature05172

Experimental method

X-RAY DIFFRACTION (4 Å)