2HW7
Crystal Structure of Mnk2-D228G in complex with Staurosporine
Summary for 2HW7
Entry DOI | 10.2210/pdb2hw7/pdb |
Related | 2AC3 2AC5 2HW6 |
Descriptor | MAP kinase-interacting serine/threonine-protein kinase 2, ZINC ION, STAUROSPORINE, ... (4 entities in total) |
Functional Keywords | protein kinases, drug, inhibitor, phosphorylation, transferase |
Biological source | Homo sapiens (human) |
Total number of polymer chains | 1 |
Total formula weight | 36136.40 |
Authors | Jauch, R.,Wahl, M.C. (deposition date: 2006-08-01, release date: 2006-08-29, Last modification date: 2023-08-30) |
Primary citation | Jauch, R.,Cho, M.K.,Netter, C.,Schreiter, K.,Aicher, B.,Zweckstetter, M.,Wahl, M.C. Mitogen-activated protein kinases interacting kinases are autoinhibited by a reprogrammed activation segment. Embo J., 25:4020-4032, 2006 Cited by PubMed: 16917500DOI: 10.1038/sj.emboj.7601285 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.71 Å) |
Structure validation
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