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2HW7

Crystal Structure of Mnk2-D228G in complex with Staurosporine

Summary for 2HW7
Entry DOI10.2210/pdb2hw7/pdb
Related2AC3 2AC5 2HW6
DescriptorMAP kinase-interacting serine/threonine-protein kinase 2, ZINC ION, STAUROSPORINE, ... (4 entities in total)
Functional Keywordsprotein kinases, drug, inhibitor, phosphorylation, transferase
Biological sourceHomo sapiens (human)
Total number of polymer chains1
Total formula weight36136.40
Authors
Jauch, R.,Wahl, M.C. (deposition date: 2006-08-01, release date: 2006-08-29, Last modification date: 2023-08-30)
Primary citationJauch, R.,Cho, M.K.,Netter, C.,Schreiter, K.,Aicher, B.,Zweckstetter, M.,Wahl, M.C.
Mitogen-activated protein kinases interacting kinases are autoinhibited by a reprogrammed activation segment.
Embo J., 25:4020-4032, 2006
Cited by
PubMed: 16917500
DOI: 10.1038/sj.emboj.7601285
PDB entries with the same primary citation
Experimental method
X-RAY DIFFRACTION (2.71 Å)
Structure validation

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