2HRC

1.7 angstrom structure of human ferrochelatase variant R115L

Summary for 2HRC

• Entry DOI: 10.2210/pdb2hrc/pdb
• Related: 2HRE
• Descriptor: Ferrochelatase, CHLORIDE ION, FE2/S2 (INORGANIC) CLUSTER, ... (7 entities in total)
• Functional Keywords: heme synthesis, ferrochelatase, protoporphyrin ix, lyase
• Biological source: Homo sapiens (human)
• Cellular location: Mitochondrion inner membrane; Peripheral membrane protein; Matrix side: P22830
• Total number of polymer chains: 2
• Total formula weight: 85372.93

Authors

Medlock, A.,Swartz, L.,Dailey, T.A.,Dailey, H.A.,Lanzilotta, W.N. (deposition date: 2006-07-20, release date: 2007-03-13, Last modification date: 2023-08-30)

• Primary citation: Medlock, A.,Swartz, L.,Dailey, T.A.,Dailey, H.A.,Lanzilotta, W.N.; Substrate interactions with human ferrochelatase; Proc.Natl.Acad.Sci.Usa, 104:1789-1793, 2007; PubMed: 17261801; DOI: 10.1073/pnas.0606144104

Experimental method

X-RAY DIFFRACTION (1.7 Å)