2HL5

Crystal structure of the C-terminal domain of human EB1 in complex with the A49M mutant CAP-Gly domain of human Dynactin-1 (p150-Glued)

Summary for 2HL5

Entry DOI	10.2210/pdb2hl5/pdb
Related	1TXQ 2HKN 2HL3 2HL5
Descriptor	Microtubule-associated protein RP/EB family member 1, Dynactin-1, CHLORIDE ION, ... (4 entities in total)
Functional Keywords	microtubule binding, dynactin, cytoskeleton associated protein, p150glued, eb1, +tip protein complex structure, structural protein
Biological source	Homo sapiens (human) More
Cellular location	Cytoplasm, cytoskeleton: Q15691 Cytoplasm: Q14203
Total number of polymer chains	4
Total formula weight	39198.58
Authors	Honnappa, S.,Winkler, F.K.,Steinmetz, M.O. (deposition date: 2006-07-06, release date: 2006-09-12, Last modification date: 2024-02-14)
Primary citation	Honnappa, S.,Okhrimenko, O.,Jaussi, R.,Jawhari, H.,Jelesarov, I.,Winkler, F.K.,Steinmetz, M.O. Key interaction modes of dynamic +TIP networks. Mol.Cell, 23:663-671, 2006 Cited by PubMed: 16949363 DOI: 10.1016/j.molcel.2006.07.013 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (1.93 Å)

Structure validation