2HH0

Structure of an Anti-PrP Fab, P-Clone, in Complex with its Cognate Bovine Peptide Epitope.

Summary for 2HH0

Entry DOI	10.2210/pdb2hh0/pdb
Descriptor	Light Chain, P-Clone Fab, Chimera, Heavy Chain, P-Clone Fab, Chimera, Prion protein, ... (4 entities in total)
Functional Keywords	prion, prp, fab, immune system
Biological source	Mus musculus, Homo sapiens (house mouse, human) More
Total number of polymer chains	3
Total formula weight	47366.76
Authors	Kanyo, Z.K. (deposition date: 2006-06-27, release date: 2006-12-26, Last modification date: 2017-10-11)
Primary citation	Luginbuhl, B.,Kanyo, Z.,Jones, R.M.,Fletterick, R.J.,Prusiner, S.B.,Cohen, F.E.,Williamson, R.A.,Burton, D.R.,Pluckthun, A. Directed evolution of an anti-prion protein scFv fragment to an affinity of 1 pM and its structural interpretation J.Mol.Biol., 363:75-97, 2006 Cited by PubMed: 16962610 DOI: 10.1016/j.jmb.2006.07.027 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.85 Å)

Structure validation