2HGX

Crystal structure of Cys315Ala mutant of human mitochondrial branched chain aminotransferase

Summary for 2HGX

Entry DOI	10.2210/pdb2hgx/pdb
Related	1EKF 1EKP 1EKV 1KT8 1KTA 2A1H 2HDK 2HG8 2HGW 2HHF
Descriptor	Branched-chain-amino-acid aminotransferase, mitochondrial, PYRIDOXAL-5'-PHOSPHATE, ACETIC ACID, ... (5 entities in total)
Functional Keywords	d-aminoacid aminotransferase-like plp-dependent enzymes, transferase
Biological source	Homo sapiens (human)
Cellular location	Isoform A: Mitochondrion. Isoform B: Cytoplasm: O15382
Total number of polymer chains	2
Total formula weight	83584.65
Authors	Yennawar, N.H.,Hutson, S.M. (deposition date: 2006-06-27, release date: 2006-10-24, Last modification date: 2021-10-20)
Primary citation	Yennawar, N.H.,Islam, M.M.,Conway, M.,Wallin, R.,Hutson, S.M. Human Mitochondrial Branched Chain Aminotransferase Isozyme: STRUCTURAL ROLE OF THE CXXC CENTER IN CATALYSIS. J.Biol.Chem., 281:39660-39671, 2006 Cited by PubMed: 17050531 DOI: 10.1074/jbc.M607552200 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (1.8 Å)

Structure validation