2HE2

Crystal structure of the 3rd PDZ domain of human discs large homologue 2, DLG2

Summary for 2HE2

• Entry DOI: 10.2210/pdb2he2/pdb
• Descriptor: Discs large homolog 2 (2 entities in total)
• Functional Keywords: dlg2, pdz, pdz domain, signal transduction, structural genomics, structural genomics consortium, sgc, signaling protein
• Biological source: Homo sapiens (human)
• Cellular location: Membrane; Lipid-anchor (By similarity): Q15700
• Total number of polymer chains: 2
• Total formula weight: 21353.78

Authors

Turnbull, A.P.,Phillips, C.,Berridge, G.,Savitsky, P.,Smee, C.E.A.,Papagrigoriou, E.,Debreczeni, J.,Gorrec, F.,Elkins, J.M.,von Delft, F.,Weigelt, J.,Edwards, A.,Arrowsmith, C.,Sundstrom, M.,Doyle, D.A.,Structural Genomics Consortium (SGC) (deposition date: 2006-06-21, release date: 2006-07-04, Last modification date: 2023-08-30)

• Primary citation: Elkins, J.M.,Papagrigoriou, E.,Berridge, G.,Yang, X.,Phillips, C.,Gileadi, C.,Savitsky, P.,Doyle, D.A.; Structure of PICK1 and other PDZ domains obtained with the help of self-binding C-terminal extensions.; Protein Sci., 16:683-694, 2007; PubMed: 17384233; DOI: 10.1110/ps.062657507

Experimental method

X-RAY DIFFRACTION (1.5 Å)