2HDM
Solution structure of V21C/V59C Lymphotactin/XCL1
Summary for 2HDM
| Entry DOI | 10.2210/pdb2hdm/pdb |
| NMR Information | BMRB: 15110 |
| Descriptor | Lymphotactin (1 entity in total) |
| Functional Keywords | lymphotactin, xcl1, chemokine, conformational restriction, cytokine |
| Biological source | Homo sapiens (human) |
| Cellular location | Secreted: P47992 |
| Total number of polymer chains | 1 |
| Total formula weight | 10195.68 |
| Authors | Volkman, B.F.,Tuinstra, R.L.,Peterson, F.C.,Elgin, E.S. (deposition date: 2006-06-20, release date: 2007-05-01, Last modification date: 2021-10-20) |
| Primary citation | Tuinstra, R.L.,Peterson, F.C.,Elgin, E.S.,Pelzek, A.J.,Volkman, B.F. An engineered second disulfide bond restricts lymphotactin/XCL1 to a chemokine-like conformation with XCR1 agonist activity Biochemistry, 46:2564-2573, 2007 Cited by PubMed: 17302442DOI: 10.1021/bi602365d PDB entries with the same primary citation |
| Experimental method | SOLUTION NMR |
Structure validation
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