2HDD

ENGRAILED HOMEODOMAIN Q50K VARIANT DNA COMPLEX

Summary for 2HDD

• Entry DOI: 10.2210/pdb2hdd/pdb
• Descriptor: DNA (5'-D(*TP*TP*TP*TP*GP*CP*CP*AP*TP*GP*TP*AP*AP*TP*CP*CP*C P*CP*GP*GP*A)-3'), DNA (5'-D(*AP*TP*CP*CP*GP*GP*GP*GP*AP*TP*TP*AP*CP*AP*TP*GP*G P*CP*AP*AP*A)-3'), PROTEIN (ENGRAILED HOMEODOMAIN Q50K), ... (4 entities in total)
• Functional Keywords: dna binding, complex (dna binding protein-dna), transcription-dna complex, transcription/dna
• Biological source: Drosophila melanogaster (fruit fly)
• Cellular location: Nucleus: P02836
• Total number of polymer chains: 4
• Total formula weight: 27738.54

Authors

Tucker-Kellogg, L.,Rould, M.A.,Chambers, K.A.,Ades, S.E.,Sauer, R.T.,Pabo, C.O. (deposition date: 1998-02-10, release date: 1998-05-27, Last modification date: 2024-02-14)

• Primary citation: Tucker-Kellogg, L.,Rould, M.A.,Chambers, K.A.,Ades, S.E.,Sauer, R.T.,Pabo, C.O.; Engrailed (Gln50-->Lys) homeodomain-DNA complex at 1.9 A resolution: structural basis for enhanced affinity and altered specificity.; Structure, 5:1047-1054, 1997; PubMed: 9309220; DOI: 10.1016/S0969-2126(97)00256-6

Experimental method

X-RAY DIFFRACTION (1.9 Å)