2H6P

Crystal structure of HLA-B*3501 presenting the human cytochrome P450 derived peptide, KPIVVLHGY

Summary for 2H6P

Entry DOI	10.2210/pdb2h6p/pdb
Descriptor	HLA-B35, Beta-2-microglobulin, 9 mer peptide from Cytochrome P450, ... (4 entities in total)
Functional Keywords	immune system, gene regulation
Biological source	Homo sapiens (human) More
Cellular location	Secreted: P61769 Endoplasmic reticulum membrane; Peripheral membrane protein: P33260
Total number of polymer chains	3
Total formula weight	44715.67
Authors	Archbold, J.K.,Macdonald, W.A.,Rossjohn, J. (deposition date: 2006-05-31, release date: 2006-09-19, Last modification date: 2011-07-13)
Primary citation	Archbold, J.K.,Macdonald, W.A.,Miles, J.J.,Brennan, R.M.,Kjer-Nielsen, L.,McCluskey, J.,Burrows, S.R.,Rossjohn, J. Alloreactivity between disparate cognate and allogeneic pMHC-I complexes is the result of highly focused, peptide-dependent structural mimicry J.Biol.Chem., 281:34324-34332, 2006 Cited by PubMed: 16963442 DOI: 10.1074/jbc.M606755200 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (1.9 Å)

Structure validation