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2H1L

The Structure of the Oncoprotein SV40 Large T Antigen and p53 Tumor Suppressor Complex

Summary for 2H1L
Entry DOI10.2210/pdb2h1l/pdb
DescriptorLarge T antigen, Cellular tumor antigen p53, ZINC ION (3 entities in total)
Functional Keywordsp53 loop-3 conformation change, viral protein
Biological sourceSimian virus 40
More
Total number of polymer chains24
Total formula weight786950.16
Authors
Lilyestrom, W.,Klein, M.G.,Chen, X.S. (deposition date: 2006-05-16, release date: 2006-09-12, Last modification date: 2023-08-30)
Primary citationLilyestrom, W.,Klein, M.G.,Zhang, R.,Joachimiak, A.,Chen, X.S.
Crystal structure of SV40 large T-antigen bound to p53: interplay between a viral oncoprotein and a cellular tumor suppressor.
Genes Dev., 20:2373-2382, 2006
Cited by
PubMed: 16951253
DOI: 10.1101/gad.1456306
PDB entries with the same primary citation
Experimental method
X-RAY DIFFRACTION (3.16 Å)
Structure validation

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