2GWR

Crystal structure of the response regulator protein mtrA from Mycobacterium Tuberculosis

Summary for 2GWR

Entry DOI	10.2210/pdb2gwr/pdb
Descriptor	DNA-binding response regulator mtrA, CALCIUM ION, GLYCEROL, ... (4 entities in total)
Functional Keywords	two-component regulatory system, transcription regulation, phosphorylation, dna-binding, ompr family, signaling protein
Biological source	Mycobacterium tuberculosis
Total number of polymer chains	1
Total formula weight	27072.97
Authors	Friedland, N.,Mack, T.R.,Yu, M.,Bursey, E.H.,Hung, L.W.,Stock, A.M.,Waldo, G.S.,Terwilliger, T.C. (deposition date: 2006-05-05, release date: 2006-05-23, Last modification date: 2017-10-18)
Primary citation	Friedland, N.,Mack, T.R.,Yu, M.,Hung, L.W.,Terwilliger, T.C.,Waldo, G.S.,Stock, A.M. Domain orientation in the inactive response regulator Mycobacterium tuberculosis MtrA provides a barrier to activation. Biochemistry, 46:6733-6743, 2007 Cited by PubMed: 17511470 DOI: 10.1021/bi602546q PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.1 Å)

Structure validation