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2GVG

Crystal Structure of human NMPRTase and its complex with NMN

Summary for 2GVG
Entry DOI10.2210/pdb2gvg/pdb
Related2GVJ
DescriptorNicotinamide phosphoribosyltransferase, PHOSPHATE ION, BETA-NICOTINAMIDE RIBOSE MONOPHOSPHATE, ... (4 entities in total)
Functional Keywordsnmprtase, visfatin, pbef, crystal, cancer, transferase
Biological sourceHomo sapiens (human)
Cellular locationCytoplasm (By similarity): P43490
Total number of polymer chains6
Total formula weight336720.64
Authors
Khan, J.A.,Tao, X.,Tong, L. (deposition date: 2006-05-02, release date: 2006-06-20, Last modification date: 2024-02-14)
Primary citationKhan, J.A.,Tao, X.,Tong, L.
Molecular basis for the inhibition of human NMPRTase, a novel target for anticancer agents.
Nat.Struct.Mol.Biol., 13:582-588, 2006
Cited by
PubMed: 16783377
DOI: 10.1038/nsmb1105
PDB entries with the same primary citation
Experimental method
X-RAY DIFFRACTION (2.2 Å)
Structure validation

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