2GPQ
Cap-free structure of eIF4E suggests basis for its allosteric regulation
Summary for 2GPQ
| Entry DOI | 10.2210/pdb2gpq/pdb |
| Descriptor | Eukaryotic translation initiation factor 4E (1 entity in total) |
| Functional Keywords | translation regulation, eif4e, apo form, translation |
| Biological source | Homo sapiens (human) |
| Total number of polymer chains | 1 |
| Total formula weight | 25130.24 |
| Authors | Volpon, L.,Osborne, M.J.,Borden, K.L.B. (deposition date: 2006-04-18, release date: 2006-11-14, Last modification date: 2022-03-09) |
| Primary citation | Volpon, L.,Osborne, M.J.,Topisirovic, I.,Siddiqui, N.,Borden, K.L. Cap-free structure of eIF4E suggests a basis for conformational regulation by its ligands. Embo J., 25:5138-5149, 2006 Cited by PubMed: 17036047DOI: 10.1038/sj.emboj.7601380 PDB entries with the same primary citation |
| Experimental method | SOLUTION NMR |
Structure validation
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