2GAQ

NMR SOLUTION STRUCTURE OF THE FRB DOMAIN OF mTOR

Summary for 2GAQ

• Entry DOI: 10.2210/pdb2gaq/pdb
• Related: 1AUE 1FAP 3FAP
• Descriptor: FKBP12-rapamycin complex-associated protein (1 entity in total)
• Functional Keywords: four helical up and down bundle, transferase
• Biological source: Homo sapiens (human)
• Cellular location: Endoplasmic reticulum membrane; Peripheral membrane protein; Cytoplasmic side: P42345
• Total number of polymer chains: 1
• Total formula weight: 12101.87

Authors

Leone, M.,Pellecchia, M. (deposition date: 2006-03-09, release date: 2006-08-08, Last modification date: 2022-03-09)

• Primary citation: Leone, M.,Crowell, K.J.,Chen, J.,Jung, D.,Chiang, G.G.,Sareth, S.,Abraham, R.T.,Pellecchia, M.; The FRB Domain of mTOR: NMR Solution Structure and Inhibitor Design.; Biochemistry, 45:10294-10302, 2006; PubMed: 16922504; DOI: 10.1021/bi060976+

Experimental method

SOLUTION NMR