2G44

Human Estrogen Receptor Alpha Ligand-Binding Domain In Complex With OBCP-1M-G and A Glucocorticoid Receptor Interacting Protein 1 NR Box II Peptide

Summary for 2G44

• Entry DOI: 10.2210/pdb2g44/pdb
• Related: 2G5O
• Descriptor: Estrogen receptor, Nuclear receptor coactivator 2, 4-[(1S,2R,5S)-4,4,8-TRIMETHYL-3-OXABICYCLO[3.3.1]NON-7-EN-2-YL]PHENOL, ... (4 entities in total)
• Functional Keywords: estrogen receptor, lbd, grip peptide, hormone-growth factor receptor complex, hormone/growth factor receptor
• Biological source: Homo sapiens (human); More
• Cellular location: Isoform 1: Nucleus. Isoform 3: Nucleus: P03372; Nucleus: Q15596
• Total number of polymer chains: 4
• Total formula weight: 62732.22

Authors

Rajan, S.S.,Hsieh, R.W.,Sharma, S.K.,Greene, G.L. (deposition date: 2006-02-21, release date: 2007-01-09, Last modification date: 2023-08-30)

• Primary citation: Hsieh, R.W.; Discovery and characterization of novel estrogen receptor agonist ligands and development of biochips for nuclear receptor drug discovery; Thesis, 2006

Experimental method

X-RAY DIFFRACTION (2.65 Å)