2FYE

Mutant Human Cathepsin S with irreversible inhibitor CRA-14013

Summary for 2FYE

• Entry DOI: 10.2210/pdb2fye/pdb
• Descriptor: cathepsin S preproprotein, N-[(1R)-1-[({[(5S)-3,5-DIMETHYL-2,5-DIHYDROISOXAZOL-4-YL]METHYL}SULFONYL)METHYL]-2-OXO-2-({(1S)-3-PHENYL-1-[2-(PHENYLSULFONYL)ETHYL]PROPYL}AMINO)ETHYL]MORPHOLINE-4-CARBOXAMIDE (3 entities in total)
• Functional Keywords: papain, cysteine protease, drug design, 14013, hydrolase
• Biological source: Homo sapiens (human)
• Cellular location: Lysosome: P25774
• Total number of polymer chains: 1
• Total formula weight: 24681.90

Authors

Somoza, J.R. (deposition date: 2006-02-07, release date: 2006-08-08, Last modification date: 2021-10-20)

• Primary citation: Somoza, J.R.; Mutant Human Cathepsin S with irreversible inhibitor CRA-14013; To be Published,

Experimental method

X-RAY DIFFRACTION (2.2 Å)