2FW4
Carbonic anhydrase activators. The first X-ray crystallographic study of an activator of isoform I, structure with L-histidine.
Summary for 2FW4
Entry DOI | 10.2210/pdb2fw4/pdb |
Descriptor | Carbonic anhydrase 1, ZINC ION, HISTIDINE, ... (4 entities in total) |
Functional Keywords | carbonic anhydrase i, activators, lyase |
Biological source | Homo sapiens (human) |
Cellular location | Cytoplasm: P00915 |
Total number of polymer chains | 2 |
Total formula weight | 57993.12 |
Authors | Temperini, C.,Scozzafava, A.,Supuran, C.T. (deposition date: 2006-02-01, release date: 2006-08-08, Last modification date: 2024-02-14) |
Primary citation | Temperini, C.,Scozzafava, A.,Supuran, C.T. Carbonic anhydrase activators: The first X-ray crystallographic study of an adduct of isoform I. Bioorg.Med.Chem.Lett., 16:5152-5156, 2006 Cited by PubMed: 16870440DOI: 10.1016/j.bmcl.2006.07.021 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2 Å) |
Structure validation
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