2FRG

Structure of the immunoglobulin-like domain of human TLT-1

Summary for 2FRG

• Entry DOI: 10.2210/pdb2frg/pdb
• Descriptor: trem-like transcript-1 (2 entities in total)
• Functional Keywords: immunoglobulin-like, beta-sandwich, cell surface receptor, triggering receptor, trem-like, platelet receptor, itim, immune system
• Biological source: Homo sapiens (human)
• Cellular location: Cell membrane ; Single-pass type I membrane protein : Q86YW5
• Total number of polymer chains: 1
• Total formula weight: 11523.27

Authors

Gattis, J.L.,Lubkowski, J. (deposition date: 2006-01-19, release date: 2006-03-14, Last modification date: 2023-08-30)

• Primary citation: Gattis, J.L.,Washington, A.V.,Chisholm, M.M.,Quigley, L.,Szyk, A.,McVicar, D.W.,Lubkowski, J.; The structure of the extracellular domain of triggering receptor expressed on myeloid cells like transcript-1 and evidence for a naturally occurring soluble fragment.; J.Biol.Chem., 281:13396-13403, 2006; PubMed: 16505478; DOI: 10.1074/jbc.M600489200

Experimental method

X-RAY DIFFRACTION (1.19 Å)