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2FIR

Crystal structure of DFPR-VIIa/sTF

Summary for 2FIR
Entry DOI10.2210/pdb2fir/pdb
Related1DAN 2A2Q 2AER 2B8O
Related PRD IDPRD_000021
DescriptorCoagulation factor VII Light chain, ZINC ION, CHLORIDE ION, ... (12 entities in total)
Functional Keywordsfactor viia, soluble tissue factor, oxyanion hole, serine protease, blood coagulation, blood clotting, hydrolase-hydrolase inhibitor complex, hydrolase/hydrolase inhibitor
Biological sourceHomo sapiens (human)
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Total number of polymer chains3
Total formula weight69134.80
Authors
Bajaj, S.P.,Schmidt, A.E.,Padmanabhan, K.,Bajaj, M.S.,Prevost, D.,Schreuder, H. (deposition date: 2005-12-30, release date: 2006-07-11, Last modification date: 2020-07-29)
Primary citationBajaj, S.P.,Schmidt, A.E.,Agah, S.,Bajaj, M.S.,Padmanabhan, K.
High Resolution Structures of p-Aminobenzamidine- and Benzamidine-VIIa/Soluble Tissue Factor: Unpredicted conformation of the 192-193 peptide bond and mapping of Ca2+, Mg2+, Na+ and Zn2+ sites in factor VIIa
J.Biol.Chem., 281:24873-24888, 2006
Cited by
PubMed: 16757484
DOI: 10.1074/jbc.M509971200
PDB entries with the same primary citation
Experimental method
X-RAY DIFFRACTION (2 Å)
Structure validation

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