2FC0

WRN exonuclease, Mn dGMP complex

Summary for 2FC0

Entry DOI	10.2210/pdb2fc0/pdb
Related	2FBT 2FBV 2FBX 2FC0
Descriptor	Werner syndrome helicase, MANGANESE (II) ION, 2'-DEOXYGUANOSINE-5'-MONOPHOSPHATE, ... (4 entities in total)
Functional Keywords	recq, wrn, werner syndrome, 3'-5' exonuclease, dnaq family, transferase
Biological source	Homo sapiens (human)
Cellular location	Nucleus, nucleolus: Q14191
Total number of polymer chains	1
Total formula weight	23887.96
Authors	Perry, J.J.,Tainer, J.A. (deposition date: 2005-12-10, release date: 2006-04-25, Last modification date: 2023-08-30)
Primary citation	Perry, J.J.,Yannone, S.M.,Holden, L.G.,Hitomi, C.,Asaithamby, A.,Han, S.,Cooper, P.K.,Chen, D.J.,Tainer, J.A. WRN exonuclease structure and molecular mechanism imply an editing role in DNA end processing. Nat.Struct.Mol.Biol., 13:414-422, 2006 Cited by PubMed: 16622405 DOI: 10.1038/nsmb1088 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2 Å)

Structure validation