2F5Z

Crystal Structure of Human Dihydrolipoamide Dehydrogenase (E3) Complexed to the E3-Binding Domain of Human E3-Binding Protein

Summary for 2F5Z

Entry DOI	10.2210/pdb2f5z/pdb
Related	1ZMC 1ZMD 2F60
Descriptor	Dihydrolipoyl dehydrogenase, Pyruvate dehydrogenase protein X component, SULFATE ION, ... (5 entities in total)
Functional Keywords	protein-protein complex, oxidoreductase-protein binding complex, oxidoreductase/protein binding
Biological source	Homo sapiens (human) More
Cellular location	Mitochondrion matrix: P09622 O00330
Total number of polymer chains	15
Total formula weight	549436.77
Authors	Brautigam, C.A.,Chuang, J.L.,Wynn, R.M.,Tomchick, D.R.,Machius, M.,Chuang, D.T. (deposition date: 2005-11-28, release date: 2006-01-17, Last modification date: 2023-08-23)
Primary citation	Brautigam, C.A.,Wynn, R.M.,Chuang, J.L.,Machius, M.,Tomchick, D.R.,Chuang, D.T. Structural Insight into Interactions between Dihydrolipoamide Dehydrogenase (E3) and E3 Binding Protein of Human Pyruvate Dehydrogenase Complex. Structure, 14:611-621, 2006 Cited by PubMed: 16442803 DOI: 10.1016/j.str.2006.01.001 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.18 Å)

Structure validation