2EXF

Solution structure of the HIV-1 nucleocapsid (NCp7(12-55)) complexed with the DNA (-) Primer Binding Site

Summary for 2EXF

• Entry DOI: 10.2210/pdb2exf/pdb
• Descriptor: 5'-D(*GP*TP*CP*CP*CP*TP*GP*TP*TP*CP*GP*GP*GP*C)-3', Nucleocapsid protein* (NC*), ZINC ION (3 entities in total)
• Functional Keywords: protein-dna complex, stem-loop, bulge, zinc-finger, viral protein-dna complex, viral protein/dna
• Total number of polymer chains: 2
• Total formula weight: 9417.39

Authors

Bourbigot, S.,Bouaziz, S.,Morellet, N. (deposition date: 2005-11-08, release date: 2007-04-24, Last modification date: 2022-03-09)

• Primary citation: Bourbigot, S.,Ramalanjaona, N.,Boudier, C.,Salgado, G.F.,Roques, B.P.,Mely, Y.,Bouaziz, S.,Morellet, N.; How the HIV-1 nucleocapsid protein binds and destabilises the (-)primer binding site during reverse transcription.; J.Mol.Biol., 383:1112-1128, 2008; PubMed: 18773912; DOI: 10.1016/j.jmb.2008.08.046

Experimental method

SOLUTION NMR