2ETX
Crystal Structure of MDC1 Tandem BRCT Domains
Summary for 2ETX
Entry DOI | 10.2210/pdb2etx/pdb |
Descriptor | Mediator of DNA damage checkpoint protein 1 (2 entities in total) |
Functional Keywords | tandem brct domains histone gamma-h2ax, cell cycle |
Biological source | Homo sapiens (human) |
Cellular location | Nucleus: Q14676 |
Total number of polymer chains | 2 |
Total formula weight | 45826.96 |
Authors | Wasielewski, E.,Kim, Y.,Joachimiak, A.,Thompson, J.R.,Mer, G. (deposition date: 2005-10-27, release date: 2005-11-15, Last modification date: 2024-02-14) |
Primary citation | Singh, N.,Wiltshire, T.D.,Thompson, J.R.,Mer, G.,Couch, F.J. Molecular Basis for the Association of Microcephalin (MCPH1) Protein with the Cell Division Cycle Protein 27 (Cdc27) Subunit of the Anaphase-promoting Complex. J.Biol.Chem., 287:2854-2862, 2012 Cited by PubMed: 22139841DOI: 10.1074/jbc.M111.307868 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.33 Å) |
Structure validation
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