2ESV

Structure of the HLA-E-VMAPRTLIL/KK50.4 TCR complex

Summary for 2ESV

• Entry DOI: 10.2210/pdb2esv/pdb
• Descriptor: HLA class I histocompatibility antigen, alpha chain E, Beta-2-microglobulin, VMAPRTLIL peptide from CMV gpUL40, ... (7 entities in total)
• Functional Keywords: t cell receptor, tcr, hla-e, cmv, pmhc-tcr complex, immune system
• Biological source: Homo sapiens (human); More
• Cellular location: Membrane; Single-pass type I membrane protein: P13747; Secreted: P61769; Membrane; Single-pass membrane protein (Potential): P01848 P01850
• Total number of polymer chains: 5
• Total formula weight: 94899.38

Authors

Hoare, H.L.,Rossjohn, J. (deposition date: 2005-10-27, release date: 2006-03-21, Last modification date: 2011-07-13)

• Primary citation: Hoare, H.L.,Sullivan, L.C.,Pietra, G.,Clements, C.S.,Lee, E.J.,Ely, L.K.,Beddoe, T.,Falco, M.,Kjer-Nielsen, L.,Reid, H.H.,McCluskey, J.,Moretta, L.,Rossjohn, J.,Brooks, A.G.; Structural basis for a major histocompatibility complex class Ib-restricted T cell response; Nat.Immunol., 7:256-264, 2006; PubMed: 16474394; DOI: 10.1038/ni1312

Experimental method

X-RAY DIFFRACTION (2.6 Å)