2ERJ

Crystal structure of the heterotrimeric interleukin-2 receptor in complex with interleukin-2

Summary for 2ERJ

Entry DOI	10.2210/pdb2erj/pdb
Descriptor	Interleukin-2 receptor alpha chain, 2-acetamido-2-deoxy-beta-D-glucopyranose, Interleukin-2 receptor beta chain, ... (10 entities in total)
Functional Keywords	interleukin-2, interleukin-2 alpha receptor, interleukin-2 beta receptor, interleukin-2 gamma receptor, immune system-cytokine complex, immune system/cytokine
Biological source	Homo sapiens (human) More
Total number of polymer chains	8
Total formula weight	196167.43
Authors	Debler, E.W.,Stauber, D.J.,Wilson, I.A. (deposition date: 2005-10-25, release date: 2006-02-21, Last modification date: 2023-08-23)
Primary citation	Stauber, D.J.,Debler, E.W.,Horton, P.A.,Smith, K.A.,Wilson, I.A. Crystal structure of the IL-2 signaling complex: Paradigm for a heterotrimeric cytokine receptor. Proc.Natl.Acad.Sci.Usa, 103:2793-, 2006 Cited by PubMed: 16477002 DOI: 10.1073/pnas.0511161103 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (3 Å)

Structure validation