2ERG

Crystal Structure of Leu3 DNA-binding domain with a single H50C mutation complexed with a 15mer DNA duplex

Summary for 2ERG

• Entry DOI: 10.2210/pdb2erg/pdb
• Related: 2ER8 2ERE
• Descriptor: 5'-D(*TP*TP*GP*CP*CP*GP*GP*TP*AP*CP*CP*GP*GP*CP*A)-3', Regulatory protein LEU3, ZINC ION, ... (4 entities in total)
• Functional Keywords: zn(2)cys(6) binuclear cluster motif, transcription activator-dna complex, transcription activator/dna
• Biological source: Saccharomyces cerevisiae (baker's yeast)
• Cellular location: Nucleus: P08638
• Total number of polymer chains: 4
• Total formula weight: 26555.68

Authors

Fitzgerald, M.X.,Marmorstein, R. (deposition date: 2005-10-24, release date: 2006-04-04, Last modification date: 2023-08-23)

• Primary citation: Fitzgerald, M.X.,Rojas, J.R.,Kim, J.M.,Kohlhaw, G.B.,Marmorstein, R.; Structure of a Leu3-DNA complex: recognition of everted CGG half-sites by a Zn2Cys6 binuclear cluster protein.; Structure, 14:725-735, 2006; PubMed: 16615914; DOI: 10.1016/j.str.2005.11.025

Experimental method

X-RAY DIFFRACTION (3.15 Å)