2E9R

Foot-and-mouth disease virus RNA-dependent RNA polymerase in complex with a template-primer RNA and with ribavirin

Summary for 2E9R

• Entry DOI: 10.2210/pdb2e9r/pdb
• Related: 1U09 1WNE 2D7S 2E9T 2E9Z 2F8E
• Descriptor: 5'-R(*CP*AP*UP*GP*GP*GP*CP*CP*C)-3', 5'-R(*CP*CP*C*GP*GP*GP*CP*CP*C)-3', RNA-dependent RNA polymerase, ... (6 entities in total)
• Functional Keywords: foot-and-mouth disease virus, rna-dependent rna polymerase, 3d polymerase, polymerase, transferase-rna complex, transferase/rna
• Biological source: Foot-and-mouth disease virus C-S8c1; More
• Cellular location: Picornain 3C: Host cytoplasm (By similarity): Q0QEE1
• Total number of polymer chains: 3
• Total formula weight: 58748.10

Authors

Ferrer-Orta, C.,Arias, A.,Perez-Luque, R.,Escarmis, C.,Domingo, E.,Verdaguer, N. (deposition date: 2007-01-26, release date: 2007-06-26, Last modification date: 2023-10-25)

• Primary citation: Ferrer-Orta, C.,Arias, A.,Perez-Luque, R.,Escarmis, C.,Domingo, E.,Verdaguer, N.; Sequential structures provide insights into the fidelity of RNA replication; Proc.Natl.Acad.Sci.Usa, 104:9463-9468, 2007; PubMed: 17517631; DOI: 10.1073/pnas.0700518104

Experimental method

X-RAY DIFFRACTION (2.81 Å)