2E59

Crystal structure of human MD-2 in complex with lipid IVa

Summary for 2E59

• Entry DOI: 10.2210/pdb2e59/pdb
• Related: 2E56
• Descriptor: Lymphocyte antigen 96, 2-acetamido-2-deoxy-beta-D-glucopyranose, (R)-((2R,3S,4R,5R,6R)-3-HYDROXY-2-(HYDROXYMETHYL)-5-((R)-3-HYDROXYTETRADECANAMIDO)-6-(PHOSPHONOOXY)TETRAHYDRO-2H-PYRAN-4-YL) 3-HYDROXYTETRADECANOATE, ... (5 entities in total)
• Functional Keywords: innate immunity, lipid-binding, lipid binding protein
• Biological source: Homo sapiens (human)
• Total number of polymer chains: 1
• Total formula weight: 18452.27

Authors

Ohto, U.,Satow, Y. (deposition date: 2006-12-19, release date: 2007-06-26, Last modification date: 2023-10-25)

• Primary citation: Ohto, U.,Fukase, K.,Miyake, K.,Satow, Y.; Crystal structures of human MD-2 and its complex with antiendotoxic lipid IVa; Science, 316:1632-1634, 2007; PubMed: 17569869; DOI: 10.1126/science.1139111

Experimental method

X-RAY DIFFRACTION (2.21 Å)