2DSR

Structural Basis for the Inhibition of Insulin-like Growth Factors by IGF Binding Proteins

Summary for 2DSR

Entry DOI	10.2210/pdb2dsr/pdb
Related	1WQJ 2DSP 2DSQ
Descriptor	Insulin-like growth factor-binding protein 4, Insulin-like growth factor IB, ... (4 entities in total)
Functional Keywords	igf, igfbp, insulin, protein binding-hormone-growth factor complex, protein binding/hormone/growth factor
Biological source	Homo sapiens (human) More
Cellular location	Secreted: P22692 P22692 P05019
Total number of polymer chains	3
Total formula weight	25280.22
Authors	Sitar, T.,Popowicz, G.M.,Siwanowicz, I.,Huber, R.,Holak, T.A. (deposition date: 2006-07-05, release date: 2006-08-22, Last modification date: 2023-10-25)
Primary citation	Sitar, T.,Popowicz, G.M.,Siwanowicz, I.,Huber, R.,Holak, T.A. Structural basis for the inhibition of insulin-like growth factors by insulin-like growth factor-binding proteins. Proc.Natl.Acad.Sci.Usa, 103:13028-13033, 2006 Cited by PubMed: 16924115 DOI: 10.1073/pnas.0605652103 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.1 Å)

Structure validation