2DOS
Structural basis for the recognition of Lys48-linked polyubiquitin chain by the Josephin domain of ataxin-3, a putative deubiquitinating enzyme
Summary for 2DOS
| Entry DOI | 10.2210/pdb2dos/pdb |
| Descriptor | Ataxin-3 (1 entity in total) |
| Functional Keywords | deubiquitinating enzyme, hydrolase |
| Biological source | Homo sapiens (human) |
| Cellular location | Nucleus matrix : P54252 |
| Total number of polymer chains | 1 |
| Total formula weight | 20162.67 |
| Authors | Sumiyoshi, A. (deposition date: 2006-05-03, release date: 2007-05-22, Last modification date: 2014-12-31) |
| Primary citation | Satoh, T.,Sumiyoshi, A.,Yagi-Utsumi, M.,Sakata, E.,Sasakawa, H.,Kurimoto, E.,Yamaguchi, Y.,Li, W.,Joazeiro, C.A.,Hirokawa, T.,Kato, K. Mode of substrate recognition by the Josephin domain of ataxin-3, which has an endo-type deubiquitinase activity. Febs Lett., 588:4422-4430, 2014 Cited by PubMed: 25448680DOI: 10.1016/j.febslet.2014.10.013 PDB entries with the same primary citation |
| Experimental method | SOLUTION NMR |
Structure validation
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