2CLQ

Structure of mitogen-activated protein kinase kinase kinase 5

Summary for 2CLQ

• Entry DOI: 10.2210/pdb2clq/pdb
• Descriptor: MITOGEN-ACTIVATED PROTEIN KINASE KINASE KINASE 5, STAUROSPORINE (3 entities in total)
• Functional Keywords: transferase, metal-binding, apoptosis
• Biological source: HOMO SAPIENS (HUMAN)
• Cellular location: Cytoplasm: Q99683
• Total number of polymer chains: 2
• Total formula weight: 67328.84

Authors

Bunkoczi, G.,Salah, E.,Fedorov, O.,Pike, A.,Gileadi, O.,von Delft, F.,Arrowsmith, C.,Edwards, A.,Sundstrom, M.,Weigelt, J.,Knapp, S. (deposition date: 2006-04-28, release date: 2006-05-09, Last modification date: 2018-01-24)

• Primary citation: Bunkoczi, G.,Salah, E.,Filippakopoulos, P.,Fedorov, O.,Muller, S.,Sobott, F.,Parker, S.A.,Zhang, H.,Min, W.,Turk, B.E.,Knapp, S.; Structural and Functional Characterization of the Human Protein Kinase Ask1.; Structure, 15:1215-, 2007; PubMed: 17937911; DOI: 10.1016/J.STR.2007.08.011

Experimental method

X-RAY DIFFRACTION (2.3 Å)