2CKE

Human death-associated DRP-1 kinase in complex with inhibitor

Summary for 2CKE

• Entry DOI: 10.2210/pdb2cke/pdb
• Related: 1WMK 1WRZ
• Descriptor: DEATH-ASSOCIATED PROTEIN KINASE 2, N-(2-AMINOETHYL)ISOQUINOLINE-5-SULFONAMIDE (3 entities in total)
• Functional Keywords: transferase-inhibitor complex, calmodulin-binding, nucleotide-binding, serine/threonine-protein kinase, apoptosis, transferase/inhibitor
• Biological source: HOMO SAPIENS (HUMAN)
• Total number of polymer chains: 4
• Total formula weight: 149671.24

Authors

Kursula, P.,Wilmanns, M. (deposition date: 2006-04-18, release date: 2007-05-15, Last modification date: 2023-12-13)

• Primary citation: Kursula, P.,Wilmanns, M.; Crystal Structure of Human Drp-1 Complexed with an Inhibitor; To be Published,

Experimental method

X-RAY DIFFRACTION (2.8 Å)