2CIA

human nck2 sh2-domain in complex with a decaphosphopeptide from translocated intimin receptor (tir) of epec

Summary for 2CIA

• Entry DOI: 10.2210/pdb2cia/pdb
• Related: 1WX6 1Z3K 2CI9
• Descriptor: CYTOPLASMIC PROTEIN NCK2, TRANSLOCATED INTIMIN RECEPTOR, (4S)-2-METHYL-2,4-PENTANEDIOL, ... (5 entities in total)
• Functional Keywords: sh2-domain, sh3 domain, phosphorylation, binding specificity
• Biological source: HOMO SAPIENS (HUMAN); More
• Total number of polymer chains: 2
• Total formula weight: 13093.56

Authors

Frese, S.,Schubert, W.-D.,Findeis, A.C.,Marquardt, T.,Roske, Y.S.,Stradal, T.E.B.,Heinz, D.W. (deposition date: 2006-03-17, release date: 2006-04-24, Last modification date: 2019-05-29)

• Primary citation: Frese, S.,Schubert, W.-D.,Findeis, A.C.,Marquardt, T.,Roske, Y.S.,Stradal, T.E.B.,Heinz, D.W.; The Phosphotyrosine Peptide Binding Specificity of Nck1 and Nck2 Src Homology 2 Domains.; J.Biol.Chem., 281:18236-, 2006; PubMed: 16636066; DOI: 10.1074/JBC.M512917200

Experimental method

X-RAY DIFFRACTION (1.45 Å)