2CG5

Structure of aminoadipate-semialdehyde dehydrogenase- phosphopantetheinyl transferase in complex with cytosolic acyl carrier protein and coenzyme A

2CG5 の概要

• エントリーDOI: 10.2210/pdb2cg5/pdb
• 関連するPDBエントリー: 2BYD 2C43
• 分子名称: L-AMINOADIPATE-SEMIALDEHYDE DEHYDROGENASE-PHOSPHOPANTETHEINYL TRANSFERASE, FATTY ACID SYNTHASE, COENZYME A, ... (7 entities in total)
• 機能のキーワード: transferase-hydrolase complex, transferase-hydrolase (complex), fatty acid biosynthesis, phosphopantetheine transferase, fasn, acp, coenzyme a, transferase, hydrolase, lipid synthesis, lyase, complex, transferase/hydrolase
• 由来する生物種: HOMO SAPIENS (HUMAN); 詳細
• 細胞内の位置: Cytoplasm : Q9NRN7 P49327
• タンパク質・核酸の鎖数: 2
• 化学式量合計: 48087.11

構造登録者

Bunkoczi, G.,Joshi, A.,Papagrigoriu, E.,Arrowsmith, C.,Edwards, A.,Sundstrom, M.,Weigelt, J.,von Delft, F.,Smith, S.,Oppermann, U. (登録日: 2006-02-27, 公開日: 2006-03-01, 最終更新日: 2023-12-13)

• 主引用文献: Bunkoczi, G.,Pasta, S.,Joshi, A.,Wu, X.,Kavanagh, K.L.,Smith, S.,Oppermann, U.; Mechanism and Substrate Recognition of Human Holo Acp Synthase.; Chem.Biol., 14:1243-, 2007; PubMed: 18022563; DOI: 10.1016/J.CHEMBIOL.2007.10.013

実験手法

X-RAY DIFFRACTION (2.7 Å)