2CDZ

CRYSTAL STRUCTURE OF THE HUMAN P21-ACTIVATED KINASE 4 IN COMPLEX WITH CGP74514A

Summary for 2CDZ

Entry DOI	10.2210/pdb2cdz/pdb
Related	2BVA
Descriptor	SERINE/THREONINE-PROTEIN KINASE PAK 4, N2-[(1R,2S)-2-AMINOCYCLOHEXYL]-N6-(3-CHLOROPHENYL)-9-ETHYL-9H-PURINE-2,6-DIAMINE, SULFATE ION, ... (5 entities in total)
Functional Keywords	transferase, protein kinase, ste20, pak4, atp-binding
Biological source	HOMO SAPIENS (HUMAN)
Cellular location	Cytoplasm : O96013
Total number of polymer chains	1
Total formula weight	34849.16
Authors	Debreczeni, J.E.,Ugochukwu, E.,Eswaran, J.,Filippakopoulos, P.,Das, S.,Fedorov, O.,Sundstrom, M.,Arrowsmith, C.,Weigelt, J.,Edwards, A.,von Delft, F.,Knapp, S. (deposition date: 2006-01-31, release date: 2006-02-08, Last modification date: 2023-12-13)
Primary citation	Eswaran, J.,Lee, W.H.,Debreczeni, J.E.,Filippakopoulos, P.,Turnbull, A.,Fedorov, O.,Deacon, S.W.,Peterson, J.R.,Knapp, S. Crystal Structures of the P21-Activated Kinases Pak4, Pak5, and Pak6 Reveal Catalytic Domain Plasticity of Active Group II Paks. Structure, 15:201-, 2007 Cited by PubMed: 17292838 DOI: 10.1016/J.STR.2007.01.001 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.3 Å)

Structure validation