2CBZ

Structure of the human Multidrug Resistance Protein 1 Nucleotide Binding Domain 1

Summary for 2CBZ

• Entry DOI: 10.2210/pdb2cbz/pdb
• Descriptor: MULTIDRUG RESISTANCE-ASSOCIATED PROTEIN 1, MAGNESIUM ION, ADENOSINE-5'-TRIPHOSPHATE, ... (4 entities in total)
• Functional Keywords: abc proteins, mrp1/abcc1, nucleotide-binding domain, atp-binding, hydrolysis, transport
• Biological source: HOMO SAPIENS (HUMAN)
• Total number of polymer chains: 1
• Total formula weight: 26433.03

Authors

Ramaen, O.,Leulliot, N.,Sizun, C.,Ulryck, N.,Pamlard, O.,Lallemand, J.-Y.,van Tilbeurgh, H.,Jacquet, E. (deposition date: 2006-01-10, release date: 2006-05-17, Last modification date: 2023-12-13)

• Primary citation: Ramaen, O.,Leulliot, N.,Sizun, C.,Ulryck, N.,Pamlard, O.,Lallemand, J.-Y.,Van Tilbeurgh, H.,Jacquet, E.; Structure of the Human Multidrug Resistance Protein 1 Nucleotide Binding Domain 1 Bound to Mg(2+)/ATP Reveals a Non-Productive Catalytic Site.; J.Mol.Biol., 359:940-, 2006; PubMed: 16697012; DOI: 10.1016/J.JMB.2006.04.005

Experimental method

X-RAY DIFFRACTION (1.5 Å)